Neomycin is a broad-spectrum bactericidal aminoglycoside antibiotic, particularly effective against
specific members of the Enterobacteriaceae family, such as Escherichia coli. It exerts its action at
the ribosomal level. When administered orally, only a small fraction (less than 5%) is absorbed into
the systemic circulation, while the majority remains in the active form within the gastrointestinal
tract of the animal. Neomycin is not rendered inactive by enzymes or affected by food. These
specific pharmacological characteristics make neomycin a highly effective antibiotic for both
preventing and treating enteric infections caused by bacteria susceptible to its action.