Florfenicol is a synthetic broad-spectrum antibiotic effective against most Gram-positive and Gram-negative
bacteria isolated from domestic animals. Florfenicol acts by inhibiting protein synthesis at the ribosomal level and
is bacteriostatic. Laboratory tests have shown that florfenicol is active against the most commonly isolated bacterial
pathogens involved in bovine respiratory disease which include Mannheimia haemolytica, Pasteurella multocida,
Histophilus somni and Arcanobacterium pyogenes, and against the bacterial pathogens most commonly isolated
in respiratory diseases in pigs, including Actinobacillus pleuropneumoniae and Pasteurella multocida.